NCT05512741

Intestinal Microbiota and Postoperative Ileus After Colorectal Surgery

Evaluation of the Role of the Intestinal Microbiota in the Mechanism of Postoperative Ileum After Colorectal Surgery : a Preliminary Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 64 (actual)
• Sponsor: University Hospital, Angers · Other Government
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Postoperative ileus (POI) after colorectal surgery is frequent and is a burden for national health authority because it increases the morbidity and the length of hospital stay. Some of the stage of the mechanism of POI are known and are now targeted to reduce its occurence but despite these measures, POI still happens in 10-30% of surgeries. The role of the intestinal microbiota in POI is unknown while it could be a new target to reduce its duration or its occurence.

Conditions

• Postoperative Ileus
• Surgery-Complications

Interventions

Type	Name	Description
OTHER	Feces collection	Feces will be collected, at home, by the patient., by using a collection kit. The stools are collected in the 2 last days before surgery. After surgery, the first stool is collected, during the hospitalization, by using the same kit. Stools are conserved in the same condition, before being frozen in our local biologic ressources center.

Timeline

• Start date: 2022-10-21
• Primary completion: 2025-05-26
• Completion: 2025-05-26
• First posted: 2022-08-23
• Last updated: 2025-06-15

Locations

1 site across 1 country: France