NCT05510908

Use of a Screening Tool to Describe HIV-Related Cancer Burden and Patient Characteristics in the AMC

Use of a Screening Tool to Describe HIV-Related Cancer Burden and Patient Characteristics in the AIDS Malignancy Consortium A Trial of the AIDS Malignancy Consortium (AMC)

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 460 (actual)
• Sponsor: AIDS Malignancy Consortium · Network
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study is being done to understand how many people with HIV (PWH) present for cancer care across the AIDS Malignancy Consortium in the United States and if there are reasons that some PWH choose to participate, or not in cancer clinical trials. Optional quality of life surveys will be used to learn more about how HIV and cancer and HIV and cancer treatment affect people.

Detailed description

Primary Objective: To estimate the number of cancers in people with HIV (PWH) who present for care at domestic AMC sites Secondary Objectives: To characterize participants that are eligible but not enrolled onto AMC clinical trials to understand site-specific and trial-specific accrual barriers Exploratory Objectives: 1. To standardize and expand the quantity and quality of sociodemographic and cancer diagnostic and treatment characteristics collected for PWH receiving care at domestic AMC sites. 2. To describe cancer patient health-related QOL for PWH at domestic AMC sites using validated tools: European Organization for Research and Treatment of Cancer Quality of Life Questionnaire \[EORTC QLQ-C30\] and Supportive Care Needs Survey Short Form 34 \[SCNS-SF34\] Outline: Participants identified via screening of electronic medical records or institutional databases. All eligible participants attend one visit for the collection of broad demographic and clinical data. Participants initiating or receiving ongoing treatment for their cancer will attend a single follow-up visit. Data collection at study visits will occur via survey procedures and/or medical record review.

Conditions

• HIV-Associated Malignant Neoplasm
• HIV Infections
• Cancer
• AIDS Related Lymphoma
• AIDS-related Kaposi Sarcoma
• AIDS-Related Malignancy
• Anal Cancer
• HPV-Related Malignancy

Interventions

Type	Name	Description
OTHER	Non-Interventional	Participants will be identified via screening of electronic medical records or institutional databases. All eligible participants will have one visit for the collection of broad demographic and clinical data. Data collection at study visit will occur via survey procedures and/or medical record review.
OTHER	Non-Interventional Follow-up	Participants initiating or receiving ongoing treatment for their cancer will attend a single follow-up visit to recollect broad demographic and clinical data. Data collection at study visits will occur via survey procedures and/or medical record review.

Timeline

• Start date: 2023-07-25
• Primary completion: 2025-02-28
• Completion: 2025-06-02
• First posted: 2022-08-22
• Last updated: 2026-03-25
• Results posted: 2026-03-25

Locations

16 sites across 2 countries: United States, Puerto Rico