NCT05510713

Blood Purification Therapy With Dual-cannula in Jugular-femoral Venous

Preliminary Study on the Effect of Blood Purification Therapy With Dual-cannula in Jugular-femoral Venous

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 50 (estimated)
• Sponsor: Shanghai Zhongshan Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Acute kidney failure (AKI) is one of the most important causes of morbidity and mortality for critical ill patients. The use of blood purification treatment such as renal replacement therapy (CRRT) and plasma exchange has gradually developed into an effective treatment. However, the efficiency of blood purification may be affected by the recirculation of dual-lumen venous catheter for some special patients including patients with vena cava reflux disorder from massive occupations or ascites. For extreme cases like patients with vena cava disconnection or severe obstruction, the traditional blood purification treatment cannot work effectively. Thus, we used the dual-cannula in jugular-femoral venous blood purification therapy in the following two patients and found that it can improve the perfusion of systemic circulation and the prognosis of patients

Conditions

• Blood Purification
• Dual-cannula
• Vena Cava Disconnection

Interventions

Type	Name	Description
DEVICE	Hemodialysis Catheter	We add a dialysis catheter to the patient, i.e., replace single-cannula in femoral venous with dual-cannula in jugular-femoral venous

Timeline

• Start date: 2022-09-01
• Primary completion: 2024-09-01
• Completion: 2024-10-01
• First posted: 2022-08-22
• Last updated: 2022-08-22