NCT05507931

Broccoli Sprouts for Mild Ulcerative Colitis

A Pilot Feasibility Study to Develop a Broccoli Sprouts-enriched Diet in the Management of Ulcerative Colitis

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 23 (actual)
• Sponsor: University of Michigan · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The goal of this study is to determine the number of servings of broccoli sprouts sufficient to (1) increase sulforaphane levels in the stool and blood and (2) reduce inflammatory markers in patients with mild ulcerative colitis. This is a pilot feasibility study to prepare for a larger randomized controlled trial.

Conditions

• Ulcerative Colitis
• Ulcerative Colitis Chronic Mild

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	1 Serving of broccoli sprouts	Participants will take 1 serving of broccoli sprouts daily for 28 days. The sprouts will be provided by the study team along with instructions on how to prepare the steamed broccoli sprouts (i.e., steamed for 10 minutes). In addition to taking the sprouts, participants will be asked to complete food diaries and surveys, collect blood and stool samples, as well as having 2 in-person visits.
DIETARY_SUPPLEMENT	3 Servings of broccoli sprouts	Participants will take 3 servings of broccoli a day for 28 days. The sprouts will be provided by the study team along with instructions on how to prepare the steamed broccoli sprouts (i.e., steamed for 10 minutes). In addition to taking the sprouts, participants will be asked to complete food diaries and surveys, collect blood and stool samples, as well as having 2 in-person visits.

Timeline

• Start date: 2023-05-23
• Primary completion: 2026-01-09
• Completion: 2026-01-09
• First posted: 2022-08-19
• Last updated: 2026-01-23

Locations

1 site across 1 country: United States