NCT05507151

Effectiveness of Endoscopic Sleeve Gastroplasty in Nonalcoholic Fatty Liver Disease/Nonalcoholic Steatohepatitis

Effectiveness of Endoscopic Sleeve Gastroplasty in Obese Patients With Nonalcoholic Fatty Liver Disease

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 30 (estimated)
• Sponsor: West Virginia University · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: —

Summary

Endoscopic weight loss procedures, also termed endoscopic sleeve gastroplasty (ESG), has been proposed as a non-surgical procedure for managing obesity and offers a standard weight loss approach. Realizing there is a knowledge gap in applying ESG to morbidly obese patients with NAFLD, the investigators propose studying the efficacy of weight control and functional outcomes of ESG. This prospective pilot study is aimed to study the safety profiles, quality of life, and changes and improvements in the anthropometric, metabolic, and biochemical changes in these patients.

Conditions

• Nonalcoholic Fatty Liver Disease

Interventions

Type	Name	Description
PROCEDURE	Endoscopic Sleeve Gastroplasty	endoscopic suturing of the stomach

Timeline

• Start date: 2022-08-24
• Primary completion: 2026-05-01
• Completion: 2026-05-01
• First posted: 2022-08-18
• Last updated: 2025-03-13

Locations

1 site across 1 country: United States