NCT05506098

Investigating STAT3 as a Driver of Pathology in Periodontitis

Investigating STAT3 as a Driver of Pathology and Potential Therapeutic Target in Periodontitis

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 28 (actual)
• Sponsor: University of Chile · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Periodontitis is a prevalent inflammatory condition that destroys tooth-supporting structures. This condition is associated with pro-inflammatory mediators that utilize STAT3 as an activator of specific genes related to inflammation and tissue destruction. STAT3 has not been studied in the context of periodontitis in humans. We propose that STAT3 is associated with periodontitis. This knowledge might help to further our understanding of periodontitis pathology

Conditions

• Periodontitis

Interventions

Type	Name	Description
OTHER	no intervention	no intervention

Timeline

• Start date: 2019-03-20
• Primary completion: 2022-10-20
• Completion: 2022-10-20
• First posted: 2022-08-18
• Last updated: 2023-01-30

Locations

1 site across 1 country: Chile