NCT05503329

Prognostic Value of Lactate Levels in Patients With STEMI Undergoing Primary PCI

Prognostic Value of Systemic Arterial Lactate Levels in Patients With ST-segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 300 (actual)
• Sponsor: Ahmed Maher Teaching Hospital · Other Government
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

To assess the prognostic value of systemic arterial lactate levels in patients with ST segment elevation myocardial infarction undergoing primary PCI and correlate with the results of primary PCI and 30 days MACE follow up.

Detailed description

* Study Population: STEMI patients treated with primary PCI. * Study period: over 6 months. * Sample Size: 300 patients. All patients received the standard care for acute STEMI patients which is the primary percutaneous intervention in addition to medications. Hyperlactemia is defined as elevated lactic acid level in the blood. The normal blood lactate level is (0.5-1 mmol/L). All subjects were subjected to 1. Careful history taking 2. Full cardiac examination 3. Investigations include: 1. 12 lead surface ECG. 2. Lactate level and full labs 3. Pre-discharge echocardiography 4. Peri-procedural details of primary PCI the investigators assessed the relation between hyperlactemia and coronary flow, peak cardiac enzymes, hemodynamic parameters and MACE in 30 days follow up

Conditions

• STEMI

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	arterial lactate level	an arterial lactate level measured from arterial sample from STEMI patients

Timeline

• Start date: 2022-01-25
• Primary completion: 2022-06-27
• Completion: 2022-06-30
• First posted: 2022-08-16
• Last updated: 2022-08-18

Locations

1 site across 1 country: Egypt