NCT05502471

Occludin and Zonulin in Attention-deficit/Hyperactivity Disorder

Serum Occludin and Zonulin Levels in Attention-deficit/Hyperactivity Disorder

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 79 (actual)
• Sponsor: Ataturk University · Academic / Other
• Sex: All
• Age: 6 Years – 12 Years
• Healthy volunteers: Accepted

Summary

The association between levels of zonulin and occludin and behavioral/emotional problems in children with ADHD are investigated.

Detailed description

Inclusion criteria for the ADHD group are (a) newly diagnosed ADHD (b) no prior psychotropic treatment for ADHD or any psychiatric disorder (c) age 6-12 years. Exclusion criteria were: (a) history of history of inflammatory/noninflammatory, metabolic, or autoimmune disease (b) any special diet history within the past year (c) use of corticosteroids or regular intake of medication in the last 6 months, (d) body mass index (BMI) \[kg/m2\] \> 30), and (e) cognitive deficits by developmental history.

Conditions

• Attention-deficit/Hyperactivity Disorder

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Zonulin	Serum zonulin level
DIAGNOSTIC_TEST	Occludin	Serum occludin level

Timeline

• Start date: 2021-01-01
• Primary completion: 2021-06-01
• Completion: 2021-06-01
• First posted: 2022-08-16
• Last updated: 2022-08-16

Locations

1 site across 1 country: Turkey (Türkiye)