Trials / Unknown
UnknownNCT05502185
Targeting Staphylococci in Atopic Dermatitis
Targeting Staphylococci Adhesion and Colonization on the Surface of Corneocytes in Atopic Dermatitis
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 60 (estimated)
- Sponsor
- L'Oreal · Industry
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Accepted
Summary
The aim of the study is to deliver a better understanding of the molecular mechanisms used by S. epidermidis strains in their adhesion and colonization on the stratum corneum across a broad spectrum of atopic dermatitis in mild to moderate conditions in adult patients.
Detailed description
Recent studies have shown that while in severe cases of AD the density of S. aureus is increased in lesions, the skin of adult patients with low to mild AD were overpopulated with S. epidermidis and not S. aureus. the aim is to characterize the S. epidermidis colonization and adhesion, with the Analyzis of skin and microbiota samples to identify and characterize S. epidermidis strains involved in corneocytes adhesion.
Conditions
Timeline
- Start date
- 2022-09-01
- Primary completion
- 2023-09-01
- Completion
- 2023-09-01
- First posted
- 2022-08-16
- Last updated
- 2022-08-16
Source: ClinicalTrials.gov record NCT05502185. Inclusion in this directory is not an endorsement.