NCT05498532

Functional MRI Evaluation in Pyeloureteral Junction Syndrome in Children

Functional MRI Usage for Pyelo-ureteral Junction Syndrome : Results of Nancy Children Hospital Cohort

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 270 (estimated)
• Sponsor: Central Hospital, Nancy, France · Academic / Other
• Sex: All
• Age: 1 Day – 17 Years
• Healthy volunteers: Not accepted

Summary

Pyelo-ureteral junction syndrome is the most common urological abnormality in children. Functional MRI has been evaluated several times, and had shown good correlation with scintigraphy, but tends to over estimate results. Moreover, those studies included a small number of cases. Its sensitivity to detect crossing polar vessel is limited. We aimed to evaluate, in patients between 0 and 1 year old, the correlation between MRI and scintigraphy differential renal function. Our secondary objectives are : evaluation of MRI performances to detect polar vessel ; comparison of surgery times depending of MRI only realisation or MRI and scintigraphy realisation.

Conditions

• Stricture of Pelviureteric Juncture

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Functional MRI	Anatomical MRI : T2 fiesta, SSFE, HASTE ; 3D T2 ; T1 FAT SAT ; LAVA Functional MRI : T1 FAT SAT with gadolinium

Timeline

• Start date: 2022-09-01
• Primary completion: 2022-09-15
• Completion: 2022-12-30
• First posted: 2022-08-12
• Last updated: 2022-08-12

Locations

1 site across 1 country: France