NCT05496829

IMPACT Trial: Intervention to iMProve AdherenCe Equitably

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 350 (estimated)
• Sponsor: Columbia University · Academic / Other
• Sex: All
• Age: 18 Years – 99 Years
• Healthy volunteers: Not accepted

Summary

To determine the efficacy of a multicomponent adherence intervention among participants with early-stage breast cancer on endocrine therapy and at least one oral cardiovascular disease (CVD) medication on adherence to endocrine therapy and to CVD medication at 24 weeks assessed by self-report using the Domains of Subjective Extent (DOSE)-Nonadherence questionnaire and also by pharmacy fill data assessed in the electronic health record (EHR).

Conditions

• Breast Cancer

Interventions

Type	Name	Description
BEHAVIORAL	Multicomponent Adherence Intervention	The adherence intervention will be comprised of a participant preference approach in which all participants undergo a baseline pharmacist-led medication optimization session and are offered training in how to use the patient portal and freely-available smartphone reminder app.
OTHER	Usual Care	Receipt of usual care from providers

Timeline

• Start date: 2023-03-02
• Primary completion: 2026-03-31
• Completion: 2027-03-31
• First posted: 2022-08-11
• Last updated: 2025-02-12

Locations

1 site across 1 country: United States