Trials / Recruiting
RecruitingNCT05496582
The Association of Transgelin-2, Metallothionein-2 and Ezrin With Asthma
The Association of Transgelin-2, Metallothionein-2 and Ezrin With Asthma: A Case-control Study
- Status
- Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 100 (estimated)
- Sponsor
- Shanghai University of Traditional Chinese Medicine · Academic / Other
- Sex
- All
- Age
- 14 Years – 75 Years
- Healthy volunteers
- Accepted
Summary
Asthma is one of the most common chronic respiratory diseases. Previous study found a series of differentially expressed genes and proteins (transgelin-2, metallothionein-2, ezrin) in asthmatic rat. The aim of the study is to investigate the changes and associations of these gene with asthma in human.
Detailed description
This study will investigate the changes and associations in asthma. In this project, the investigators will explore the changes of gene expression of transgelin-2, metallothionein-2 and ezrin in asthma and investigate their correlation with current diagnosis markers of asthma, including pulmonary function, fractional exhaled nitric oxide,eosinophil counts,immunoglobulin E, interleukin-5, etc.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIAGNOSTIC_TEST | No intervention | No intervention |
Timeline
- Start date
- 2022-11-01
- Primary completion
- 2026-08-01
- Completion
- 2026-12-01
- First posted
- 2022-08-11
- Last updated
- 2024-05-08
Locations
2 sites across 1 country: China
Source: ClinicalTrials.gov record NCT05496582. Inclusion in this directory is not an endorsement.