Clinical Trials Directory

Trials / Completed

CompletedNCT05495451

Feasibility and Impact of an Intensive Team-based Intervention on Type 2 Diabetes Reversal

Status
Completed
Phase
N/A
Study type
Interventional
Enrollment
36 (actual)
Sponsor
Montreal Heart Institute · Academic / Other
Sex
All
Age
18 Years – 80 Years
Healthy volunteers
Not accepted

Summary

To evaluate the feasibility of a 6-month multidisciplinary program to reverse type 2 diabetes using the Mediterranean diet, intermittent fasting and exercise.

Detailed description

The morbidities associated with type 2 diabetes (Db2) are major, including cardiovascular and renal complications, but also cognitive impairment. Providing interventions targeting Db2 reversal has shown great potential to improve healthy aging. A Db2 reversal clinic has been established at the Montreal Heart Institute's ÉPIC Center, with an approach based on the Mediterranean diet and exercise. First-year results showed a 0.6% decrease in Hb1Ac and an average weight loss at 3 months of 4.5 kg in diabetic patients. This improvement was maintained at 6 and 12 months. Although these results are encouraging, the literature in Db2 remission shows that a weight loss of 10 kg is the ideal goal. Therefore, to offer the possibility of further metabolic improvement at 6 months, three interventions are proposed as additions to the current program: targeting ultra-processed food reduction, motivational coaching and intermittent fasting. The main objective of our pilot study is to determine the feasibility of this improved program in type 2 diabetic patients, aged 18 to 80 years.

Conditions

Interventions

TypeNameDescription
BEHAVIORALModerate-carbohydrate Mediterranean diet, Personalized exercice prescription and training, Intermittent fastingMultidisciplinary program will provide the teaching and supervision necessary to integrate the new knowledge and commitment to these lifestyle changes.

Timeline

Start date
2022-01-21
Primary completion
2023-03-21
Completion
2023-05-21
First posted
2022-08-10
Last updated
2023-11-21

Locations

1 site across 1 country: Canada

Source: ClinicalTrials.gov record NCT05495451. Inclusion in this directory is not an endorsement.