NCT05494931

Effect of Superficial Keratotomy on Reducing Postoperative Pain Fallowing Conjuctival Flap

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 9 (actual)
• Sponsor: Iran University of Medical Sciences · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Accepted

Summary

During conjunctival flap surgery the corneal epithelium is removed and a conjunctival flap is placed on the cornea and after a few weeks the conjunctiva covers the surface of the eye. Complications of this operation are flap retraction, conjunctival inclusion cysts, bleeding, infection and pain. Pain is one of the main complications of conjunctival flap surgery. Two sources are conceivable for pain: 1) conjunctival pain 2) corneal pain, the second of which is the main part of the pain. Numerous methods for controlling corneal pain have been reported in various articles. Eye patches are often recommended for the treatment of corneal abrasions despite the lack of evidence. Recommended analgesics to control corneal scratch pain include nonsteroidal anti-inflammatory drugs (NSAIDs), local anesthetics, and topical cycloplegias. In this article, we are going to review and evaluate a new method called corneal neuorotomy, i.e., corneal nerve endings that inserted radially can be cut to reduce postoperative pain.

Detailed description

The main idea of this randomized clinical trial is to test the extent of pain relief after incision of radial corneal nerve endings. Patients are divided into two groups. In the first group, the same classic method of conjunctival flap surgery was used and in the second group, conjunctival flap surgery was performed adjuncted by cutting the radial superficial nerves of the cornea. The postoperative pain scores of these two groups will be measured using visual analogue scale, after 6 hours, 24 hours and 48 hours, and finally the average pain of the two groups will be compared.

Conditions

• Reduced Corneal Sensation

Interventions

Type	Name	Description
PROCEDURE	corneal neurotomy	Classic Gunderson conjunctival flap surgery adjuncted by corneal neurotomy

Timeline

• Start date: 2020-12-15
• Primary completion: 2022-06-05
• Completion: 2022-08-05
• First posted: 2022-08-10
• Last updated: 2022-08-10

Locations

1 site across 1 country: Iran