NCT05492786

High-risk Influenza Vaccine Alert

Alerts With Risk Information to Increase Influenza Vaccinations

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 80,452 (actual)
• Sponsor: Geisinger Clinic · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to assess, prospectively, the effect on flu vaccination rates of salient alerts in the electronic health record that indicate a patient's high risk for flu and its complications. The investigators hypothesize that the salient alerts will lead to increased flu vaccination compared with a standard flu alert.

Detailed description

The CDC (Centers for Disease Control) recommends a flu vaccination to everyone aged 6+ months, with rare exception; almost anyone can benefit from the vaccine, which can reduce illnesses, missed work, hospitalizations, and death. One barrier to vaccination is a lack of "cues to action," and, in particular, the lack of direct recommendation from medical personnel; this barrier is arguably the most effectively overcome by a simple nudge of clinicians, compared with barriers such as negative attitudes toward vaccination, low perceived utility of vaccination, and less experience with having received the vaccine. Geisinger partnered with Medial EarlySign (Medial) to develop a machine learning (ML) algorithm to help identify people at risk for serious flu-associated complications based on existing electronic health record data. Eligible at-risk patients will be randomized to an active control group (clinician will be shown a standard flu alert) or one of two experimental groups (clinician will be shown an alert indicating patient's high risk, with or without describing the patient's factors contributing to that risk).

Conditions

• Influenza

Interventions

Type	Name	Description
BEHAVIORAL	Alert	Non-interruptive best practice alert in the electronic health record
BEHAVIORAL	Salient alert features	Larger alert header and body font size, use of different font colors and boldface
BEHAVIORAL	High-risk Text	Alert header indicates patient is at high risk for flu and its complications; alert body indicates the percentage of risk (e.g., in the top 3% of risk)
BEHAVIORAL	Risk factors	Alert body indicates the top 3 factors contributing to the high risk

Timeline

• Start date: 2022-09-01
• Primary completion: 2023-04-01
• Completion: 2023-04-01
• First posted: 2022-08-09
• Last updated: 2024-12-30
• Results posted: 2024-05-06

Locations

1 site across 1 country: United States