NCT05491343

Observation vs Progesterone Treatment for Management of Uterine Arteriovenous Malformation

Management of Uterine Arteriovenous Malformation- a Comparison of 2 Management Possibilities- Observation vs. Progesterone Treatment/ a Randomized Control Trial

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 28 (estimated)
• Sponsor: HaEmek Medical Center, Israel · Academic / Other
• Sex: Female
• Age: 18 Years – 50 Years
• Healthy volunteers: Not accepted

Summary

A randomized trial which compares conservative management to progesterone based treatment for arteriovenous malformation

Conditions

• Arteriovenous Malformations

Interventions

Type	Name	Description
DRUG	MedroxyPROGESTERone Injection [Depo-Provera]	The drug-induced endometrial changes would likely to prevent the shedding of endometrium, in turn preventing the exposure of AVM.
DEVICE	Other	Follow up using US

Timeline

• Start date: 2022-08-01
• Primary completion: 2022-12-01
• Completion: 2024-01-01
• First posted: 2022-08-08
• Last updated: 2022-08-08

Regulatory

• FDA-regulated drug study
• FDA-regulated device study