NCT05487131

Neuromodulation and Fatigue

Neuromodulation and Its Effects on Muscle Activity and Fatigue

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: University of Oklahoma · Academic / Other
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: Accepted

Summary

In this project, we aim to determine any potential effects of a weak electrical current applied to the neck or thoracic area on functional capacity and muscle activation. Healthy individuals will participate in one familiarization followed by up to 6 experimental sessions. Fatigability and motor function will be assessed in each test session.

Detailed description

This project will investigate the potential impact of an electrical current of low intensity, and applied non-invasively, on the signals that drive muscle contractions. Individuals will receive distinct types of stimulation that vary depending on the direction on the current (anodal vs cathodal) and placement of the electrodes. These conditions will be compared to a sham stimulation. The test session will be randomized in a double blind fashion, which indicates that neither participants or investigators will know the type of stimulation. Motor function and the muscle electrical activity will be quantified during each test session.

Conditions

• Healthy Aging
• Fatigue

Interventions

Type	Name	Description
BEHAVIORAL	electrical stimulation	different types of low-intensity (comfortable) electrical stimulation will be used and applied in distinct locations

Timeline

• Start date: 2023-06-03
• Primary completion: 2027-09-01
• Completion: 2027-12-01
• First posted: 2022-08-04
• Last updated: 2026-04-09

Locations

1 site across 1 country: United States