Trials / Completed
CompletedNCT05479786
Reproductive Outcomes After a Previous Episode of Tubal Ectopic Pregnancy in Patients Managed Expectantly and Surgically
Evaluation of Reproductive Outcomes After Expectant or Surgical Management of a Previous Episode of Tubal Ectopic Pregnancy
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 312 (actual)
- Sponsor
- University of Palermo · Academic / Other
- Sex
- Female
- Age
- 18 Years – 45 Years
- Healthy volunteers
- Not accepted
Summary
Although ectopic pregnancy was considered a leading cause of first-trimester maternal mortalities, current technological improvements allowed early diagnosis and opened a door for applying less invasive approaches. A tubal pregnancy could be managed either expectantly, medically, or surgically. The expectant management of ectopic pregnancy relies on the fact that a considerable proportion of ectopic gestations terminate by spontaneous tubal abortion. This approach is usually kept for stable cases with a small gestational sac and low beta-human chorionic gonadotropin (beta-HCG) serum levels. For hemodynamically unstable patients, higher levels of beta-HCG, and larger gestational sacs, surgery is often considered as the treatment of choice (16). Considering this background, the study aims to analyze the subsequent natural reproductive outcomes of patients that had a previous tubal ectopic pregnancy and were managed either expectantly or surgically. Moreover, it amis to determine the factors that could influence the fertility potential of these patients in each treatment group.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Expectant management | Follow-up with beta-HCG dosages and transvaginal ultrasound scans |
| PROCEDURE | Salpingectomy | Removal of the affected Fallopian tube by laparoscopy |
| PROCEDURE | Salpingostomy | Removal of the ectopic pregnancy from the Fallopian tube, without removing the whole Fallopian tube, by laparoscopy |
Timeline
- Start date
- 2012-01-01
- Primary completion
- 2020-12-31
- Completion
- 2020-12-31
- First posted
- 2022-07-29
- Last updated
- 2022-08-02
Source: ClinicalTrials.gov record NCT05479786. Inclusion in this directory is not an endorsement.