Trials / Recruiting
RecruitingNCT05478694
Outcomes of Focal Ablation for Prostate Cancer
Prospective Single Institutional Study Evaluating the Outcomes for Patients Undergoing Ablative Therapies in the Management of Clinically Localized Prostate Cancer in the Primary and Salvage Setting
- Status
- Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 225 (estimated)
- Sponsor
- University of Texas Southwestern Medical Center · Academic / Other
- Sex
- Male
- Age
- 18 Years – 90 Years
- Healthy volunteers
- Not accepted
Summary
This study will be designed to define the efficacy and safety of ablative therapies in the management of localized prostate cancer and comprehensively evaluate quality of life outcomes and oncologic control following treatment.
Detailed description
This study will be designed to define the efficacy and safety of ablative therapies in the management of localized prostate cancer and comprehensively evaluate quality of life outcomes and oncologic control following treatment. There are several commercially available standard of care treatments available for local therapy of the prostate. Ablative therapies may be delivered via a whole gland or focal approach by systems including cryoablation (CA), brachytherapy, irreversible electroporation (IRE), high intensity focused ultrasound (HIFU), MRI-guided transurethral ultrasound ablation (TULSA) procedure or future novel prostate ablation systems. These are single, outpatient treatments lasting between 2-4 hours and include treatment planning and energy delivery under guidance and are either administered via transperineally approach (cryoablation, IRE, brachytherapy) or via the urethral (TULSA-Pro) or rectum (HIFU). This study protocol will not include experimental therapy and the enrolled subjects will undergo the ablative therapy as part of their standard of care treatment.
Conditions
Timeline
- Start date
- 2023-02-01
- Primary completion
- 2026-08-01
- Completion
- 2026-08-01
- First posted
- 2022-07-28
- Last updated
- 2026-04-17
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT05478694. Inclusion in this directory is not an endorsement.