Clinical Trials Directory

Trials / Completed

CompletedNCT05477121

Severity: Quantifying the Severity of Generalized Tonic-clonic Seizures (GTCS) With Connected Devices

Status
Completed
Phase
Study type
Observational
Enrollment
400 (actual)
Sponsor
Centre Hospitalier Universitaire Vaudois · Academic / Other
Sex
All
Age
12 Years
Healthy volunteers
Not accepted

Summary

By bringing together the fields of seizure detection and that of Sudden Unexpected Death in Epilepsy (SUDEP), the current project aims at delineating which set of biosensors and related biomarkers would optimally characterize the severity of GTCS and the associated risk of SUDEP.

Detailed description

The main objective is to to evaluate which of the five biosignals considered, being, electrodermal activity (EDA), heart rate (HR), accelerometry (AC), arm-measurement of skin electromyography (EMG), and bed sensing of body movement (BM), or any of their combinations, offers the most accurate detection and quantification of our primary indicator of GTCS-severity, i.e. postictal EEG suppression (PGES).

Conditions

Timeline

Start date
2019-06-12
Primary completion
2023-12-31
Completion
2024-12-31
First posted
2022-07-28
Last updated
2025-02-18

Locations

1 site across 1 country: Switzerland

Source: ClinicalTrials.gov record NCT05477121. Inclusion in this directory is not an endorsement.