Trials / Active Not Recruiting
Active Not RecruitingNCT05477082
Blood Biomarkers in Pediatric Kidney Transplant Recipients
Use of Blood Gene Expression Profile and Donor-derived Cell-free DNA to Monitor Response to Treatment After Biopsy-proven Acute Rejection in Pediatric Kidney Transplant Recipients
- Status
- Active Not Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 27 (actual)
- Sponsor
- University of Minnesota · Academic / Other
- Sex
- All
- Age
- 21 Years
- Healthy volunteers
- Not accepted
Summary
The objective of the proposed study is to assess whether a blood biomarker can be used to monitor the response to rejection treatment in pediatric kidney transplant recipients with biopsy-proven acute cellular or antibody mediated rejection. The study hypothesizes that blood gene expression profile and donor-derived cell-free DNA biomarkers (omnigraf) can be used to predict acute rejection and monitor its response to treatment.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Observational group | Includes blood draws and data collection only |
Timeline
- Start date
- 2023-08-21
- Primary completion
- 2025-11-16
- Completion
- 2026-11-01
- First posted
- 2022-07-28
- Last updated
- 2025-12-17
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT05477082. Inclusion in this directory is not an endorsement.