NCT05473975

Search for a Recanalization of the Sylvian Artery Electro-Physiological Biomarker

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 15 (actual)
• Sponsor: Fondation Ophtalmologique Adolphe de Rothschild · Network
• Sex: All
• Age: 18 Years
• Healthy volunteers: —

Summary

Early recanalization is a major prognostic factor in vascular accidents ischemic brain injury (AIC). The acute phase therapies of AIC aim to recanalization by intravenous thrombolysis and/or mechanical thrombectomy. Recanalization is identified immediately during thrombectomy by per-procedural arteriography. For the thrombolysis, only a performed MRI will validate the recanalization. This "proof of concept" study aims to identify an Electro-Encephalographic biomarker (EEG) of the recanalization in real time, the EEG being easy to set up. This biomarker will be sought during recanalization certified by thrombectomy in order to identify the window time for which the biomarker must be sought on the EEG. During this study, the identified EEG biomarker can be used to validate the recanalization during the intravenous thrombolysis in future studies

Conditions

• AIS

Interventions

Type	Name	Description
PROCEDURE	Placement of the EGG	Placement of the EGG before the beginning of the thrombectomy

Timeline

• Start date: 2023-01-24
• Primary completion: 2025-01-23
• Completion: 2025-01-23
• First posted: 2022-07-26
• Last updated: 2025-06-25

Locations

1 site across 1 country: France