NCT05467774

Operant H-reflex Down-conditioning of Rectus Femoris in Post-stroke Stiff Knee Gait

• Status: Completed
• Phase: EARLY_Phase 1
• Study type: Interventional
• Enrollment: 7 (actual)
• Sponsor: University of Texas at Austin · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Accepted

Summary

The investigators performed a feasibility trial of operant conditioning of spinal reflex excitability on five healthy individuals and two post-stroke individuals. The investigators found that operant conditioning of rectus femoris reflex excitability was feasible in all participants.

Detailed description

The investigators performed a cohort study on 7 individuals (5 healthy, 2 post-stroke) to examine the feasibility of operant down-conditioning of rectus femoris reflex excitability (i.e. H-reflex). Each individual performed 30 sessions, 6 baseline sessions with no operant conditioning (225 trials of surface electrical stimulation of the femoral nerve), followed by 24 training sessions (20 baseline trials followed by 225 trials with feedback of H-reflex magnitude). The investigators' main outcome measure was rectus femoris H-reflex magnitude. We also examined H-reflex magnitude of other quadriceps muscles.

Conditions

• Training

Interventions

Type	Name	Description
BEHAVIORAL	Operant RF H-reflex conditioning	Operant down-conditioning of rectus femoris H-reflex

Timeline

• Start date: 2018-07-28
• Primary completion: 2020-02-17
• Completion: 2020-02-17
• First posted: 2022-07-21
• Last updated: 2024-07-16
• Results posted: 2024-07-16

Locations

1 site across 1 country: United States