NCT05467384

Effect of Amlodipine on the Lipid Profile of Newly Diagnosed Hypertensive Patients

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 80 (actual)
• Sponsor: Ayub Teaching Hospital · Academic / Other
• Sex: All
• Age: 20 Years – 60 Years
• Healthy volunteers: Accepted

Summary

In this study, Amlodipine has been used to study its effects in newly diagnosed hypertensive patients.

Detailed description

The incidence of hypertension is on the rise in developing countries like Pakistan. Different medications are used to decrease blood pressure with Amlodipine as one of the first-line drugs. It was proposed that due to interaction with calcium and thus luminal cholecystokinin releasing factor; Amlodipine might increase the cholesterol level and thus cause dyslipidemia. Objective: In this regard, this study was conducted to look into the effects of Amlodipine in newly diagnosed cases of hypertension that had received no medication previously. Methodology: Experimental study with a healthy control group with the sample size calculated out to be 80, comprising of an equal number of enrolment into case and control groups.

Conditions

• Hypercholesterolemia
• Hypertension
• Cholesterol Deposition

Interventions

Type	Name	Description
DRUG	Amlodipine	5mg/day in two divided doses

Timeline

• Start date: 2016-03-01
• Primary completion: 2017-06-30
• Completion: 2017-06-30
• First posted: 2022-07-20
• Last updated: 2022-07-20