Trials / Recruiting
RecruitingNCT05466786
Distribution of the Homologous Recombination-related (HRR) Genesmutationsand HRD in Breast Cancer
Landscape Ofhomologous Recombination-related (HRR) Genes Mutations and HRD, and Correlation With Survival in HER2-lowbreast Cance
- Status
- Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 255 (estimated)
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Academic / Other
- Sex
- Female
- Age
- 18 Years – 70 Years
- Healthy volunteers
- Not accepted
Summary
This is a cross-sectional and an observational study, investigator-initiated study in HER2-low breast cancer patients. Approximately 255 subjects with HRD (homologous recombination deficiency) assessment will be enrolled in this study to examine the distribution and features of HRD/HRR (homologous recombination repair). In this study, investigators plan to clarify the frequency of HRR/HRD in Chinese patients with HER2-low breast cancer. In addition, it is planned to investigate any association between invasive disease-free survival (iDFS)/overall survival (OS) and HRD/HRR in HER2-low breast cancer patients.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Standard Management | Standard Management |
Timeline
- Start date
- 2022-08-07
- Primary completion
- 2027-05-31
- Completion
- 2027-05-31
- First posted
- 2022-07-20
- Last updated
- 2025-10-03
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT05466786. Inclusion in this directory is not an endorsement.