NCT05466591

Pre-hospital Rule-out of Acute Coronary Syndrome

Acute Rule Out of Non ST-segment Elevation Acute Coronary Syndrome in the (Pre)Hospital Setting by HEART Score Assessment and a Single Point-of-care Troponin

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 866 (actual)
• Sponsor: Radboud University Medical Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Patients with chest pain suspected for non ST-segment elevation acute coronary syndrome (NSTE-ACS) are routinely transferred to the emergency department (ED). A point-of-care (POC) troponin measurement might enable ambulance paramedics to identify low-risk patients in whom ED evaluation is not necessary. The ARTICA trial aims to assess the healthcare cost reduction and safety of a pre-hospital rule-out strategy using a single POC troponin measurement.

Detailed description

Patients with chest pain suspected of a NSTE-ACS are screened by ambulance paramedics. The HEAR score (HEART score without the Troponin component) is assessed and patients with a HEAR score of ≤3 are included. The patients are randomised to 1) pre-hospital rule-out with POC troponin measurement (intervention group) and 2) direct transfer to the ED (standard care group). Primary outcome is healthcare costs after 30 days.

Conditions

• Acute Coronary Syndrome

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Pre-hospital rule-out strategy	Point-of-care troponin measurement for pre-hospital rule-out of acute coronary syndrome

Timeline

• Start date: 2019-03-01
• Primary completion: 2022-06-04
• Completion: 2023-05-04
• First posted: 2022-07-20
• Last updated: 2022-07-25

Locations

1 site across 1 country: Netherlands