NCT05465252

Effect of Omega-3 Fatty Acid Supplementation on Dry-AMD Progression

Effect of Krill Oil Supplementation on Dry Age-Related Macular Degeneration: A Randomized Controlled Trial

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 24 (estimated)
• Sponsor: Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine · Academic / Other
• Sex: All
• Age: 50 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

This randomized, double-blind, placebo-controlled study aims to evaluate the effect of krill oil supplementation in patients with dry age-related macular degeneration (AMD). Participants will receive 4 capsules of krill oil or placebo daily for a period of 3 months. Outcomes will be evaluated after 3-month treatment to assess differences between the two study groups.

Conditions

• Age-Related Macular Degeneration

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Krill Oil	Qualified subjects start to take supplementation from Day 1 in the trial. Specifically, subjects from Intervention group take 4 capsules of krill oil per day.
DIETARY_SUPPLEMENT	Olive Oil	Qualified subjects start to take placebo from Day 1 in the trial. Specifically, subjects from placebo group take 4 capsules of olive oil, which has the same color and smell as the krill oil.

Timeline

• Start date: 2025-10-17
• Primary completion: 2026-03-01
• Completion: 2026-05-01
• First posted: 2022-07-19
• Last updated: 2026-01-02

Locations

1 site across 1 country: China