NCT05464771

The Impact of Patient Safety Incidents on Patients' Quality of Life

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 395,346 (actual)
• Sponsor: Imperial College London · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: —

Summary

This study estimates the impact of patient safety events on QoL in elective surgery patients using a secondary data set

Detailed description

Background: The burden of patient safety incidents (PSIs) is often characterised by their impact on mortality, morbidity and treatment costs. Few studies have attempted to estimate the impact of PSIs on patients' health-related quality of life (HRQoL) and the studies that have made such estimates primarily focus on a narrow set of incidents. The aim of this paper is to estimate the impact of PSIs on HRQoL of patients undergoing elective surgery in England. Materials and Methods: A unique linked longitudinal data set consisting of Patient Reported Outcome Measures (PROMS) for patients with hip and knee replacements linked to Hospital Episode Statistics (HES) collected between 2013/14 and 2016/17 is examined. Patients with any of nine US Agency for Healthcare Research and Quality (AHRQ) PSI indicators are identified. HRQoL is measured using the general EuroQol five dimensions questionnaire (EQ-5D) before and after surgery. Exploiting the longitudinal structure of the data, exact matching combined with difference in differences to estimate the impact of experiencing a PSI on HRQoL and its individual dimensions, comparing HRQoL improvements after surgery in similar patients with and without a PSI.

Conditions

• Hip Fractures
• Knee Fracture

Interventions

Type	Name	Description
PROCEDURE	Surgery for hip and knee replacement	Elective inpatient surgery for hip and knee replacement

Timeline

• Start date: 2018-12-01
• Primary completion: 2020-12-01
• Completion: 2021-12-01
• First posted: 2022-07-19
• Last updated: 2022-07-27

Locations

1 site across 1 country: United Kingdom