Trials / Completed
CompletedNCT05458843
Renal Considerations in the Heat Stress Recommendations (Aim2)
Renal Considerations in the Heat Stress and Hydration Recommendations (Aim 2)
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 18 (actual)
- Sponsor
- Indiana University · Academic / Other
- Sex
- All
- Age
- 18 Years – 44 Years
- Healthy volunteers
- Accepted
Summary
An epidemic of chronic kidney disease is occurring in laborers who undertake physical work outdoors in hot conditions. The reason for this is largely unknown, but may be related to kidney dysfunction caused by increases in body temperature and dehydration that elicit oxidative stress and inflammation in the renal tubules. The purpose of this study is to determine whether hydration status modifies the development of renal oxidative stress and inflammation.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Fluid replacement | Participants will drink Gatorade Zero ad libitum, up to 1 cup every 15 minutes. |
| PROCEDURE | No fluid replacement | Participants will not be permitted to drink. |
Timeline
- Start date
- 2022-08-01
- Primary completion
- 2023-05-22
- Completion
- 2023-05-22
- First posted
- 2022-07-14
- Last updated
- 2023-11-08
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT05458843. Inclusion in this directory is not an endorsement.