NCT05458635

Predictors of Pulmonary Hypertension in Patients With Hypersensitivity Pneumonitis

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: Cairo University · Academic / Other
• Sex: All
• Age: 29 Years – 55 Years
• Healthy volunteers: Not accepted

Summary

Hypersensitivity pneumonitis (HP) is a complex immune mediated disorders caused by repeated inhalation of and sensitization to wide range of antigens including organic particles and chemical compounds, leading to exaggerated immuneresponse. Hypersenstivity pneumonitis is a common form of diffuse parenchymal lung diseases in Egypt .Pulmonary hypertension has been found as a complication of a number of diseases affecting the lung interstitium, including hypersensitivity pneumonitis, with subsequent affection of the life expectancy Rationale of the study: to find predictors for the development of pulmonary hypertension in patients with hypersensitivity pneumonitis

Detailed description

Cross sectional study included 60 patients with established diagnosis of HP , work up includes history of exposure, clinical examination, HRCT chest, ABGs,6MWD, desaturation degree , spirometry, echocardiography and right heart catheter in patients with high echo probability of PH.

Conditions

• Pulmonary Hypertension
• Hypersensitivity Pneumonitis

Interventions

Type	Name	Description
PROCEDURE	Right heart catheter	Right heart catheterization was performed for 4 cases with high probability of pulmonary hypertension using multi-lumen swan ganz catheter.

Timeline

• Start date: 2019-08-01
• Primary completion: 2020-10-31
• Completion: 2021-03-15
• First posted: 2022-07-14
• Last updated: 2022-07-14

Locations

1 site across 1 country: Egypt