NCT05458388

Different Endoscopic Gastric Cancer Risk Assessments

Different Endoscopic Gastric Cancer Risk Assessments for the Detection of Early Gastric Cancer

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 3,500 (estimated)
• Sponsor: Yanqing Li · Academic / Other
• Sex: All
• Age: 40 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

The Kimura-Takamoto classification established in Japan can observe the extent of gastric atrophy in real-time under endoscopy, and diffuse atrophy also indicates an increased risk of gastric cancer. Recent studies have found that the evaluation of intestinal metaplasia score (EGGIM score) of various stomach parts by electronic staining can well identify OLGIM III\\ IV patients. Although the Kimura-Takamoto classification and EGGIM score can evaluate the risk of gastric cancer in patients, only in cross-sectional studies, it is not clear the diagnostic value of risk assessment in population screening. Early gastric cancer has the characteristics of hidden lesions and a high rate of clinical missed diagnosis. Concentrating high-risk groups through risk scores is expected to guide endoscopic doctors to conduct a targeted careful examination. However, it is not clear whether Kimura-Takamoto classification and EGGIM score can improve the detection rate of early gastric cancer in clinical practice.

Conditions

• Gastric Cancer Screening

Interventions

Type	Name	Description
PROCEDURE	Kimura-Takemoto classification	All patients were given two risk scores, the order of which was randomly determined.
PROCEDURE	EGGIM	All patients were given two risk scores, the order of which was randomly determined.

Timeline

• Start date: 2022-07-12
• Primary completion: 2024-12-31
• Completion: 2025-07-04
• First posted: 2022-07-14
• Last updated: 2022-07-14

Locations

1 site across 1 country: China