NCT05457374

A Clinical Study of Portal Vein Embolization and Liver Venous Deprivation

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 10 (estimated)
• Sponsor: Anhui Provincial Hospital · Other Government
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

The main obstacle to achieving R0 resection in future liver remnant（FLR） deficient liver cancer is the inability to retain sufficient FLR to avoid postoperative liver failure. From the initial portal vein embolization(PVE), to the later ALPPS, this problem has been solved to some extent. However, both have their own shortcomings. The effect of liver hyperplasia after PVE is poor and the waiting time is long. The incidence of complication and mortality after ALPPS is always the focus of controversy. In recent years, LVD has emerged, combining PVE and HVE in the one operation. This topic will conduct a clinical controlled study of PVE and LVD.

Conditions

• Liver Venous Deprivation

Interventions

Type	Name	Description
PROCEDURE	PVE	Portal vein embolization (PVE) mainly embolizes the portal vein of the resected liver lobe, causing the non-tumor lobe to proliferate, and after tumor lobectomy, the volume of the non-tumor lobe proliferates so that patients with hepatocellular carcinoma that could not be directly surgically resected are given the opportunity to be surgically resected
PROCEDURE	LVD	Combining PVE and Hepatic Vein Embolization (HVE) in the same procedure

Timeline

• Start date: 2022-03-01
• Primary completion: 2024-03-01
• Completion: 2025-03-01
• First posted: 2022-07-14
• Last updated: 2022-07-14

Locations

1 site across 1 country: China