Clinical Trials Directory

Trials / Unknown

UnknownNCT05457114

Association Between the Use of Pulmonary Artery Catheter and Clinical Outcomes After Liver Transplantation

Status
Unknown
Phase
Study type
Observational
Enrollment
1,970 (estimated)
Sponsor
Seoul National University Hospital · Academic / Other
Sex
All
Age
20 Years
Healthy volunteers
Not accepted

Summary

The investigators attempted to evaluate whether the use of PAC is associated with better clinical outcomes after liver transplantation compared with the case without PAC.

Detailed description

Pulmonary artery catheter (PAC) has been used for advanced hemodynamic monitoring during liver transplantation. However, recent advances in less invasive monitoring could provide continuous cardiac output monitoring by arterial waveform analysis. Using this technology, stroke volume variation (SVV) is monitored as a preload index. Calculated systemic vascular resistance (SVR) can be monitored if central venous pressure (CVP) is provided. Therefore, this less invasive form of hemodynamic monitoring may replace the PAC. The investigators attempted to evaluate whether the use of PAC is associated with better clinical outcomes after liver transplantation compared with the case without PAC.

Conditions

Interventions

TypeNameDescription
DEVICEPulmonary artery catheter (Edward Lifesciences, Irvine, California, USA)PAC was inserted and connected to a continuous cardiac output monitor (Vigilance I from 2006 to 2012; Vigilance II from 2012 to 2022, Edward Lifesciences, Irvine, USA)
DEVICEFloTrac Vigileo system (EV1000 clinical platform, Edward Lifesciences, Irvine, California, USA)Without PAC, monitoring with FloTrac Vigileo system (EV1000 clinical platform, Edward Lifesciences, Irvine, California, USA) was performed for continuous cardiac output monitoring.

Timeline

Start date
2022-05-01
Primary completion
2022-12-31
Completion
2022-12-31
First posted
2022-07-13
Last updated
2022-07-15

Locations

1 site across 1 country: South Korea

Source: ClinicalTrials.gov record NCT05457114. Inclusion in this directory is not an endorsement.