NCT05455528

Preoperative Renal Insufficiency Predicts Postoperative Adverse Outcomes

Preoperative Renal Insufficiency Predicts Postoperative Adverse Outcomes: A Matched Cohort Study Using the NSQIP Database

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 2,421,286 (actual)
• Sponsor: Taipei Medical University Hospital · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

The main purpose of this study is to evaluate the risk of postoperative mortality and complications in surgical populations with preoperative renal insufficiency.

Detailed description

This retrospective cohort study use the National Surgical Quality Improvement Program (NSQIP) database to evaluate the risk of postoperative morbidity and mortality in the surgical population. Patients with estimated. glomerular filtration rate(GFR) \< 60 ml/min per 1.73 square meter are defined as the renal insufficiency group. Patients with estimated GFR \> 90 ml/min per 1.73 square meter are defined as patients without renal insufficiency. Propensity score-matching methods and multivariate logistic regression are used to calculate the risk of postoperative morbidity and mortality.

Conditions

• Renal Insufficiency
• Morality

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	estimated GFR calculation	The estimated GFR is computed with Modification of Diet in Renal Disease (MDRD) formula

Timeline

• Start date: 2022-01-01
• Primary completion: 2022-06-30
• Completion: 2022-07-01
• First posted: 2022-07-13
• Last updated: 2022-07-13

Locations

1 site across 1 country: Taiwan