NCT05455177

Change in Patient Reported Outcomes and Wish for Joint Surgery

Within-person Change in Patient-reported Outcomes and Their Association With the Wish to Undergo Joint Surgery During a Digital First-line Intervention for Osteoarthritis

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 14,018 (actual)
• Sponsor: Joint Academy · Industry
• Sex: All
• Age: —
• Healthy volunteers: —

Summary

Aim To investigate associations between within-person change in patient reported outcomes (PROMs) and wish for joint surgery during up to 12-month participation in a digital first-line intervention for knee and hip osteoarthritis (OA) comprising exercise and education. Methods Retrospective observational registry data. All participants enrolling between June 1st 2018 and September 30th 2021 with follow-up data and with a change in their wish for surgery (dichotomous, becoming wishing or unwishing) were included. Analysed PROMS comprised pain (numeric rating scale (NRS), 0-10), 5 level EuroQol - 5-dimension (EQ5D-5L, 0.243-0.976), overall health (NRS, 0-10), activity impairment (NRS, 0-10), walking difficulties (yes/no), fear of movement (yes/no), function and quality of life subscales of Knee/Hip injury and Osteoarthritis Outcome Score 12 Items (KOOS-12/HOOS-12, both 0-100). To capture effects of changes in PROMs over time on probability of wish for surgery, the investigators used fixed effect (conditional) logistic regressions.

Conditions

• Osteoarthritis, Knee and Hip

Interventions

Type	Name	Description
OTHER	Digital first-line intervention for osteoarthritis including exercise and education	The digital OA management programme was delivered by a smartphone application, including education and exercises based on a face-to-face osteoarthritis self-management programme provided nationwide in Sweden and designed according to national and international guidelines. Over 12 weeks, which is the recommended minimum duration of a self-management intervention for OA, a total of 163 exercise sessions and 31 educational sessions are provided.

Timeline

• Start date: 2018-06-01
• Primary completion: 2021-09-30
• Completion: 2021-09-30
• First posted: 2022-07-13
• Last updated: 2022-07-27

Locations

1 site across 1 country: Sweden