NCT05454644

Effectiveness of a Person-centred Prescription Model at the End of Life

Effectiveness of a Person-centred Prescription Model in Hospitalised Geriatric Patients at the End of Life

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 114 (actual)
• Sponsor: Matia Foundation · Academic / Other
• Sex: All
• Age: 65 Years
• Healthy volunteers: Not accepted

Summary

This study's main objective is to investigate whether the application of an adapted person-centred prescription model during a hospital stay would reduce the use of inappropriate or futile regular medications in older people at the end of life, improving their clinical/health statuses and reducing the expense associated with pharmacological treatment. We hypothesised that applying this modified method could optimise pharmacotherapeutic indicators and the expense associated with the pharmacological treatment of hospitalised patients

Conditions

• End-Of-Life
• Inappropriate Prescribing
• Deprescriptions
• Palliative Medicine
• Geriatrics

Interventions

Type	Name	Description
OTHER	Person-Centred Prescription Model	Step 1: Identify patients with advanced chronic condition and limited life expectancy. Step 2: Interview with patients or closes caregiver. Step 3: Medication Review The clinical pharmacist conduct a structured medication review based on the medication appropriateness index (MAI): * Indication/effectiveness: Product information, STOPPFrail (Screening Tool of Older Persons' Prescriptions in Frail adults with limited life expectancy) criteria and Beers Criteria for Potentially Inappropriate Medication Use in Older Adults. * Dosage adjustment: Product Information and Lexi-Comp's Geriatric Dosage Handbook. * Correct and practical directions: Medication Regimen Complexity Index (MRCI). * Drug-drug interactions: Bot Plus/Beers Criteria and drug burden index (DBI), which measures dose-dependent anticholinergic and sedative loads. * Drug-disease interactions: Beers Criteria. * Duplication, duration and cost-effectiveness: Product information. Step 4: Treatment Plan

Timeline

• Start date: 2018-02-15
• Primary completion: 2020-02-28
• Completion: 2021-02-28
• First posted: 2022-07-12
• Last updated: 2022-07-12

Locations

1 site across 1 country: Spain