NCT05453929

Deep Neuromuscular Block on Postoperative Delirium in Lumbar Surgery

Effect of the Deep Neuromuscular Block on Postoperative Delirium in Elderly Patients Undergoing Lumbar Surgery

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 230 (actual)
• Sponsor: Korea University Guro Hospital · Academic / Other
• Sex: All
• Age: 70 Years
• Healthy volunteers: Not accepted

Summary

The effect of deep neuromuscular blockade (NMB) during spine surgery reduced postoperative pain and bleeding in recent studies. Therefore by reducing these two factors, which were the contributing factors for postoperative delirium, deep NMB is expected to reduce the postoperative delirium. This study was designed to determine whether the deep NMB lowered the incidence of delirium after lumbar surgery.

Conditions

• Lumbar Spine Disease

Interventions

Type	Name	Description
DRUG	Rocuronium for deep NMB	Deep neuromuscular blockade will be maintained using continuous infusion of rocuronium.
DRUG	Rocuronium for moderate NMB	Moderate neuromuscular blockade will be maintained using continuous infusion of rocuronium.

Timeline

• Start date: 2021-09-16
• Primary completion: 2024-12-20
• Completion: 2025-01-02
• First posted: 2022-07-12
• Last updated: 2025-01-03

Locations

1 site across 1 country: South Korea