NCT05451745

Glaucoma Following Pediatric Cataract Surgery

Incidence of and Risk Factors for Glaucoma Following Pediatric Cataract Surgery: 10 Years Longitudinal Study

• Status: Active Not Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 819 (actual)
• Sponsor: Sun Yat-sen University · Academic / Other
• Sex: All
• Age: 3 Months – 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to report the incidence and related risk factors glaucoma following cataract surgery (GFCS). and to provide evidence-based evidence for the development of standardized follow-up methods or diagnosis and treatment decisions.

Detailed description

A secondary clinical data analysis from a prospective longitudinal cohort study. A total of 819 children with congenital cataracts (CC) were included from January 2011 to December 2016, and the follow-up deadline was January 31, 2022. All study subjects were under 18 years old, and the average follow-up time after cataract extraction was over 5 years. The children were divided into subgroups according to whether the intraocular lens (IOL) was implanted or not after cataract surgery, and the clinical characteristics were compared. Cox regression analysis model and Kaplan-Meier survival analysis model were used to investigate the incidence, cumulative risk probability and related risk factors of GFCS events. A nomogram was used to build a predictive model for the occurrence of GFCS.

Conditions

• Glaucoma Following Pediatric Cataract Surgery
• Glaucoma Secondary
• Congenital Cataract

Timeline

• Start date: 2011-01-01
• Primary completion: 2022-01-01
• Completion: 2032-01-01
• First posted: 2022-07-11
• Last updated: 2022-07-11