NCT05450497

Effect of Sedative Agent on Reducing the Frequency of Arrhythmia in the Patients After Cardiac Surgery

Effect of Propofol vs Dexmedetomidine or Propofol+Dexmedetomidine on Reducing the Frequency of Arrhythmia in Patients After Cardiac Surgery

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 356 (actual)
• Sponsor: Anesthesia Research Group UA · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Arrhythmias early in the recovery period after cardio thoracic surgery are common they develop in 11 to 40 percent of patients after coronary-artery bypass grafting. The right chose of sedative agent could decrease the level of arrhythmia incidence.

Detailed description

Arrhythmias are really common in patients after cardiac surgery. Most of the patients get sedation after cardiac surgery. The goal is to determine if the propofol (PR) (sedative agent), dexmedetomidine (DEX)(selective α2-adrenergic receptor (α2-AR) agonist) or their combination could improve and decrease the incidence of the arrhythmia in patients after cardiac surgery.

Conditions

• Arrythmia

Interventions

Type	Name	Description
DRUG	Propofol	comparing sedative agents
DRUG	Dexmedetomidine	comparing sedative agents
DRUG	Dexmedetomidine and propofol	comparing sedative agents

Timeline

• Start date: 2017-07-01
• Primary completion: 2019-07-01
• Completion: 2019-07-01
• First posted: 2022-07-08
• Last updated: 2022-07-08

Locations

1 site across 1 country: Ukraine