NCT05447130

Corneal Endothelium After Phacoemulsification in Pseudo Exfoliation Syndrome

Corneal Endothelial Evaluation After Phacoemulsification in Eyes With Pseudoexfoliation Syndrome

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (actual)
• Sponsor: Minia University · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

To study corneal endothelial cells changes after phacoemulsification in patients with senile cataract and pseudoexfoliation syndrome (PEX) compared with control patients with senile cataract using specular microscope.

Detailed description

In a prospective interventional case-control study, 20 eyes with cataract and PEX and 20 control eyes with cataract without PXE were subjected to phacoemulsification and posterior chamber foldable intraocular lens implantation in Minia University Hospital and Genaidy Eye Center between March 2019 and December 2020. Specular microscopy was done preoperatively, 3 and 6 months postoperatively. Endothelium cell density (ECD), coefficient variation (CV), hexagonality, pleomorphism and corneal thickness were evaluated and compares between PXE and control eyes.

Conditions

• Corneal Endothelial Cell Loss
• Pseudoexfoliation Syndrome

Interventions

Type	Name	Description
PROCEDURE	phacoemulsification	phacoemulsification with corneal endothelial evaluation by specular microscopy

Timeline

• Start date: 2019-03-01
• Primary completion: 2020-12-20
• Completion: 2020-12-31
• First posted: 2022-07-07
• Last updated: 2022-09-13

Locations

1 site across 1 country: Egypt