NCT05446402

Investigation of the Tolerability of Two Facial Cleansing Routines for Mild to Moderate Acne

Double Blinded, Split Face Investigation of the Tolerability of Two Facial Cleansing Routines for Mild to Moderate Acne

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 29 (actual)
• Sponsor: Northwestern University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The objective of this study is to compare tolerability of two similar commercially available over the counter acne regimens (Geologie and Proactiv) in individuals with mild to moderate acne vulgaris over a 12-week daily treatment course.

Detailed description

Acne vulgaris is a common, chronic inflammatory skin disorder that originates in the pilosebaceous unit. Acne typically begins in adolescence and often continues into adulthood, with about 20% of cases resulting in scars or hyperpigmentation. It's estimated that acne affects about 85% of adolescents. Individuals who experience acne and acne scars tend to also experience a negative impact on their social and mental health, including depression, anxiety, and social withdrawal. Currently, topical solutions and lifestyle changes are the primary treatment for mild to moderate acne. This study will evaluate and compare the efficacy of two over the counter products in treating individuals with mild to moderate acne: Geologie and ProActive. Both sets of products will be provided to Northwestern in identical, unlabeled bottles for the purpose of blinding.

Conditions

• Acne

Interventions

Type	Name	Description
COMBINATION_PRODUCT	Geologie Acne Regimen - one side of face	Geologie is an over-the-counter cosmetic acne regimen with three products. The regimen also has three "levels" over the course of three months, in which the nighttime lotion is switched to a stronger formula each month. The Geologie Clear System regimen for acne prone skin includes: 1. Clarifying Gel Cleanser - SA Formula (2% Salicylic Acid) 2. Brightening Day Cream - SPF 15 (5% Azelaic Acid, 2% Hyaluronic Acid, 1%Niacinamide) 3. Repairing Night Cream - 1. Level 1 (0.05% Retinol, 3% Niacinamide, 2% Hyaluronic Acid) 2. Level 2 (0.2% Retinol, 3% Niacinamide, 2% Hyaluronic Acid) 3. Level 3 (0.3% Retinol, 3% Niacinamide, 2% Hyaluronic Acid)
COMBINATION_PRODUCT	Proactive Acne Regimen - other side of face	ProActiv is an over-the-counter cosmetic regimen with three products. The Proactiv Solution 3-Piece System regimen includes: 1. Renewing Cleanser (Active ingredient: 2.5% Benzoyl Peroxide) 2. Revitalizing Toner (Glycolic Acid) 3. Repairing Treatment (Active ingredient: 2.5% Benzoyl Peroxide)

Timeline

• Start date: 2022-06-15
• Primary completion: 2023-05-31
• Completion: 2023-12-31
• First posted: 2022-07-06
• Last updated: 2024-04-11

Locations

1 site across 1 country: United States