NCT05445505

Neuroprotective Effects of iTBS in PD

Neuroprotective Effects of Intermittent Theta Burst Stimulation in Parkinson's Disease: a Delayed-start Randomized Double-blind Sham Controlled Study

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Ruijin Hospital · Academic / Other
• Sex: All
• Age: 20 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Intermittent theta burst stimulation (iTBS) is an emerging non-invasive neuron regulation technique, which is widely used in neuropsychiatry for a variety of diseases and is widely accepted by patients due to its non-invasive, operable and relatively precise localization. Combining the results of previous studies and our group's previous research, sixty qualified PD patients would be enrolled to conduct a prospective single-center randomized double-blind sham controlled clinical trial to verify the long-term curative effects of iTBS treatment protocol and explore the neuron-protection of iTBS on neuronal loss of PD patients.

Conditions

• Neuroprotection
• Parkinson Disease
• Intermittent Theta Burst Stimulation

Interventions

Type	Name	Description
DEVICE	intermittent theta burst stimulation	iTBS is a new form of excitatory rTMS treatment that is less time-consuming and more effective than traditional rTMS in a single treatment session.
DEVICE	sham iTBS	The pseudo-stimulation device looks and sounds the same as the iTBS device

Timeline

• Start date: 2022-08-01
• Primary completion: 2024-06-30
• Completion: 2024-12-31
• First posted: 2022-07-06
• Last updated: 2023-05-09

Locations

1 site across 1 country: China