NCT05444699

Oral Prednisolone for Acute Rhinovirus Induced Wheezing in Children Less Than 2 Years of Age

Oral Prednisolone for Acute Rhinovirus Induced Wheezing in Children Less Than 2 Years of Age: a Point-of-care Testing Guided Randomized, Double-blind, Placebo-controlled Trial

• Status: Recruiting
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 210 (estimated)
• Sponsor: University of Oulu · Academic / Other
• Sex: All
• Age: 6 Months – 24 Months
• Healthy volunteers: Not accepted

Summary

The aim of the trial is to evaluate whether the use of oral prednisolone directed by point-of-care testing is useful in acute wheezing caused by rhinovirus in children aged 6-24 months.

Conditions

• Bronchiolitis Acute Viral

Interventions

Type	Name	Description
DRUG	Prednisolone Sodium Phosphate	Oral suspension administered 1 mg/kg once a day for three days
DRUG	Sugar syrup	Oral suspension administered the same amount in milliliters as experimental product once a day for three days

Timeline

• Start date: 2022-10-11
• Primary completion: 2026-12-01
• Completion: 2027-09-01
• First posted: 2022-07-06
• Last updated: 2025-02-13

Locations

2 sites across 1 country: Finland