NCT05442931

Comparison Between Pregabalin and Magnesium Sulfate in Hypotensive Anaesthesia

Comparison Between Single Dose Pregabalin and Magnesium Sulfate in Controlled Hypotension During Functional Endoscopic Sinus Surgery

• Status: Unknown
• Phase: Phase 1 / Phase 2
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Minia University · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

Comparison between pregabalin and magnesium sulfate in hypotensive anaethesia

Detailed description

compare the effect of a single-dose 150 mg oral pregabalin and 2 grams intravenous magnesium sulfate given 30 minutes before induction of anesthesia on the total nitroglycerine used in patients undergoing functional endoscopic sinus surgery

Conditions

• Functional Endoscopic Sinus Surgery

Interventions

Type	Name	Description
DRUG	Pregabalin 150mg	The oral tablet half an hour preoperative 150 milligrams
DRUG	Magnesium Sulfate	Intravenous administration half an hour preoperative 2 grams
DRUG	Nitroglycerin	measure total dose of nitroglycerine in milligrams using a syringe pump
OTHER	surgeon satisfaction	surgeon satisfaction measured according to Likert's scale

Timeline

• Start date: 2022-05-01
• Primary completion: 2022-10-30
• Completion: 2022-10-30
• First posted: 2022-07-05
• Last updated: 2022-07-05

Locations

1 site across 1 country: Egypt

Regulatory

• FDA-regulated drug study
• FDA-regulated device study