Clinical Trials Directory

Trials / Terminated

TerminatedNCT05441826

Efficacy and Safety of VB119 in Subjects With Minimal Change Disease (MCD) and Focal Segmental Glomerulosclerosis (FSGS)

A Phase 2 Study of VB119 in Adult Subjects With Steroid-Sensitive Primary Minimal Change Disease (MCD) or Primary Focal Segmental Glomerulosclerosis (FSGS)

Status
Terminated
Phase
Phase 2
Study type
Interventional
Enrollment
1 (actual)
Sponsor
Tenet Medicines · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

Phase 2, multi-center, proof-of-concept study to evaluate the safety and efficacy of VB119 on the maintenance of remission and duration of response in adults with primary MCD or primary FSGS who previously responded to steroid therapy.

Conditions

Interventions

TypeNameDescription
DRUGVB119Humanized, immunoglobin (Ig) G1 monoclonal antibody (mAb) to be administered as intravenous infusion at multiple timepoints during the study.

Timeline

Start date
2022-05-03
Primary completion
2023-05-03
Completion
2023-10-12
First posted
2022-07-01
Last updated
2024-04-22

Locations

1 site across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT05441826. Inclusion in this directory is not an endorsement.