Clinical Trials Directory

Trials / Completed

CompletedNCT05441501

A Study of JNJ-80038114 in Participants With Advanced Stage Prostate Cancer

A Phase 1 Study of JNJ-80038114, a T-Cell Redirecting Agent Targeting Prostate Specific Membrane Antigen (PSMA), for Advanced Stage Prostate Cancer

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
39 (actual)
Sponsor
Janssen Research & Development, LLC · Industry
Sex
Male
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to determine recommended phase 2 dose(s) (RP2Ds) of JNJ-80038114 in Part 1 (dose escalation) and to determine the safety at the RP2D(s) in Part 2 (dose expansion).

Conditions

Interventions

TypeNameDescription
DRUGJNJ-80038114JNJ-80038114 will be administered.

Timeline

Start date
2022-11-15
Primary completion
2024-03-26
Completion
2024-03-31
First posted
2022-07-01
Last updated
2025-03-04

Locations

6 sites across 2 countries: United States, United Kingdom

Regulatory

Source: ClinicalTrials.gov record NCT05441501. Inclusion in this directory is not an endorsement.