NCT05437198

Study of Microbiological Diversity in Exhaled Air in COPD and Free of COPD

Study of Microbiological Diversity in Exhaled Air in Adult Subjects With Chronic Obstructive Pulmonary Disease (COPD) and Subjects Free of COPD

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 240 (estimated)
• Sponsor: Centre Hospitalier Intercommunal Creteil · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

COPD and non-COPD patients will be included in the study after collection of their non-objection. The exhalation will be collected to study the microbiological diversity of human exhalations. a second collection for the year +1 will be made, at the same time (between October and March).

Detailed description

The subjects will be recruited during a medical visit in the Departments of Pneumology and Occupational and Environmental Pathologies. After information and inclusion of the subject in the study, a collection of clinical data, the state of health and the smoking status of the subject will be carried out by the clinical study technician. A collection of the exhalation will also be carried out by the clinical study technician. Several groups of subjects will be formed according to pathologies (COPD versus non-COPD), age and smoking status

Conditions

• Chronic Obstructive Pulmonary Disease

Interventions

Type	Name	Description
OTHER	collection of human exhalation	the collection of the exhalation will be carried out with a non-invasive device manufactured by a Chinese company. The collection of exhalation consists of the subject inhaling through the nose and exhaling gently through the mouth through a plastic straw for a time set at 5 min in the device

Timeline

• Start date: 2024-03-26
• Primary completion: 2028-03-01
• Completion: 2029-03-01
• First posted: 2022-06-29
• Last updated: 2025-06-12

Locations

1 site across 1 country: France