NCT05435599

Serum Regucalcin Level and Chronic Hepatitis B

Efficacy of Serum Regucalcin Level in Detecting Fibrosis in Chronic Hepatitis B Infection

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 120 (actual)
• Sponsor: Konya Meram State Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

This study, it was aimed to investigate the relationship between serum regucalcin level and liver fibrosis level in patients with CHB infection.

Detailed description

Chronic hepatitis B (CHB) infection continues to be an important health problem due to its high morbidity and mortality. For this reason, it is very important to determine the appropriate timing to start antiviral therapy in patients with CHB infection and to evaluate the stage of liver fibrosis in the treatment follow-up. Liver biopsy is the gold standard for detecting liver fibrosis. Although it is generally accepted to be a safe procedure, it can cause some serious complications. For this reason, in recent years, many studies have been conducted on new noninvasive tests in the evaluation of liver fibrosis. One of them is the serum regucalcin level. Studies have shown that serum regucalcin levels increase in liver damage, but there is no study in the literature comparing liver fibrosis and serum regucalcin levels in CHB infection. This study, it was aimed to investigate the relationship between serum regucalcin level and liver fibrosis level in patients with CHB infection.

Conditions

• Chronic Hepatitis b
• Liver Fibrosis

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Serum regucalcin level	During routine outpatient controls, serum regucalcin level will be measured from the rest of the blood taken for examinations.

Timeline

• Start date: 2020-08-01
• Primary completion: 2020-12-31
• Completion: 2021-12-01
• First posted: 2022-06-28
• Last updated: 2022-06-28

Locations

1 site across 1 country: Turkey (Türkiye)