NCT05434520

Relieving the Bile Ducts Prior to Pancreatoduodenectomy

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 722 (actual)
• Sponsor: Rigshospitalet, Denmark · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: —

Summary

The aim of this study was to assess the risk and complications after preoperative drainage of biliary obstruction in patients who underwent pancreatoduodenectomy. A retrospective cohort study of all patients who underwent pancreatoduodenectomy from January 1st, 2015 to September 30th, 2021. Patients who had preoperative bile duct drainage were compared to patients without intervention. Type of interventions, complications and outcome after surgery were compared using univariate and multivariate analysis.

Detailed description

Obstructive jaundice is a common problem in pancreatic and periampullary tumors, but preoperative biliary drainage in patients with hyperbilirubinemia is still controversial. The aim of this retrospective cohort study was to assess the risk and complications after preoperative drainage of biliary obstruction in patients who underwent pancreatoduodenectomy. A retrospective cohort study of all patients who underwent pancreatoduodenectomy from January 1st, 2015 to September 30th, 2021.

Conditions

• Pancreas Cancer
• Surgery-Complications
• Biliary Fistula

Interventions

Type	Name	Description
PROCEDURE	Preoperative biliary drainage (ERC og PTC-aided)	Placement of biliary stent (plastic, covered SEMS, uncovered SEMS) endoscopic by ERC or placement of plastic catheter by PTC

Timeline

• Start date: 2021-03-01
• Primary completion: 2022-03-01
• Completion: 2022-03-01
• First posted: 2022-06-28
• Last updated: 2022-06-28

Locations

1 site across 1 country: Denmark