NCT05433870

Inflammatory Biomarkers for the Diagnosis of oPRES

Inflammatory Biomarkers for the Diagnosis of Obstetric Posterior Reversible Encephalopathy Syndrome

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 621 (actual)
• Sponsor: Dunjin Chen · Academic / Other
• Sex: Female
• Age: 16 Years – 50 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to explore the inflammatory biomarkers for the diagnosis of obstetric posterior reversible encephalopathy syndrome.

Detailed description

The investigators retrospectively collected data (General information, clinical data, biochemical indicators, imaging features, and pregnancy outcome) from pregnant woman diagnosed with PRES to explore the inflammatory biomarkers for the diagnosis of oPRES during 2012 to 2021.Then, the investigators grouped all the patients into PRES group (PE or E with PRES) and NOT-PRES group (PE or E without PRES) according to the diagnostic criteria of PRES. Then, the investigators analysed the inflammatory biomarkers, such as neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), monocyte-lymphocyte ratio (MLR), and so on of two groups, and compared the difference of tow groups.

Conditions

• Posterior Reversible Encephalopathy Syndrome
• Inflammatory Biomarkers
• Neutrophil-lymphocyte Ratio

Interventions

Type	Name	Description
OTHER	Whether the PE or E patient combined with PRES	According to the Diagnostic criteria of PRES, all the patients grouped into two groups.

Timeline

• Start date: 2022-07-01
• Primary completion: 2022-07-31
• Completion: 2022-07-31
• First posted: 2022-06-27
• Last updated: 2022-08-03

Locations

1 site across 1 country: China